Evaluation of analgesic activity of allopurinol and febuxostat in experimental analgesic models in mice

Evaluation of analgesic activity of allopurinol and febuxostat in experimental analgesic models in mice

Background: Allopurinol and febuxostat are xanthine oxidase inhibitors which are used in the treatment of hyperuricemia and gout. Pain is one of the important symptoms in gout patients. The present study was to evaluate the analgesic activity of allopurinol and febuxostat in two analgesic models in...

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Bibliographic Details
Main Authors: Promod D Shankpal, J H Hotwani, Kunal A Chitnis, Dnyanesh S Tadke, Vijay R Kokani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Indian Journal of Pain
Subjects:
Allopurinol
Eddy′s hot plate method
febuxostat
nonsteroidal anti-inflammatory drugs
reactive oxygen species
writhing method
Online Access:http://www.indianjpain.org/article.asp?issn=0970-5333;year=2015;volume=29;issue=2;spage=106;epage=110;aulast=Shankpal

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http://www.indianjpain.org/article.asp?issn=0970-5333;year=2015;volume=29;issue=2;spage=106;epage=110;aulast=Shankpal

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