The role of mTOR pathway as target for treatment in adrenocortical cancer

Adrenocortical carcinomas (ACCs) are rare tumors with scant treatment options for which new treatments are required. The mTOR pathway mediates the intracellular signals of several growth factors, including the insulin-like growth factors (IGFs), and therefore represents a potential attractive pathwa...

Full description

Bibliographic Details
Main Authors: Maria Cristina De Martino, Richard A Feelders, Claudia Pivonello, Chiara Simeoli, Fortuna Papa, Annamaria Colao, Rosario Pivonello, Leo J Hofland
Format: Article
Language:English
Published: Bioscientifica 2019-09-01
Series:Endocrine Connections
Subjects:
Online Access:https://ec.bioscientifica.com/view/journals/ec/8/9/EC-19-0224.xml