Nicotinamide attenuates streptozotocin-induced diabetes complications and increases survival rate in rats: role of autonomic nervous system

Abstract Background To evaluate the effect of nicotinamide prior to streptozotocin-induced (STZ) diabetes in baroreflex sensitivity and cardiovascular autonomic modulation, and its association with hemodynamics and metabolic parameters. Methods Methods: Male Wistar rats were divided into control (Co...

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Main Authors: Paula L. Cruz, Ivana C. Moraes-Silva, Amanda A. Ribeiro, Jacqueline F. Machi, Marcelo Dantas Tavares de Melo, Fernando dos Santos, Maikon Barbosa da Silva, Celia Maria Cassaro Strunz, Elia Garcia Caldini, Maria-Claudia Irigoyen
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Endocrine Disorders
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Online Access:https://doi.org/10.1186/s12902-021-00795-6