A Noninvasive Intratracheal Inoculation Method for the Study of Pulmonary Melioidosis

Pulmonary melioidosis, a disease manifestation caused by the bacterium Burkholderia pseudomallei, has been studied using aerosols or intranasal inoculation in small animal models. Both have inherent disadvantages which may not accurately model primary pulmonary melioidosis in humans. Intratracheal...

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Bibliographic Details
Main Authors: David Aaron Revelli, Julie A Boylan, Frank C Gherardini
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-12-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2012.00164/full