Unraveling the molecular basis of host cell receptor usage in SARS-CoV-2 and other human pathogenic β-CoVs

Unraveling the molecular basis of host cell receptor usage in SARS-CoV-2 and other human pathogenic β-CoVs

The recent emergence of the novel SARS-CoV-2 in China and its rapid spread in the human population has led to a public health crisis worldwide. Like in SARS-CoV, horseshoe bats currently represent the most likely candidate animal source for SARS-CoV-2. Yet, the specific mechanisms of cross-species t...

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Bibliographic Details
Main Authors: Camila Pontes, Victoria Ruiz-Serra, Rosalba Lepore, Alfonso Valencia
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
SARS-CoV-2
Spike protein evolution
Phylogenetic analysis
Protein subfamilies
Functional specificity
Specificity Determining Positions
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037021000106

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http://www.sciencedirect.com/science/article/pii/S2001037021000106

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