Thiol-free chemoenzymatic synthesis of β-ketosulfides

A preparation of β-ketosulfides avoiding the use of thiols is described. The combination of a multicomponent reaction and a lipase-catalysed hydrolysis has been developed in order to obtain high chemical diversity employing a single sulfur donor. This methodology for the selective synthesis of a set...

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Bibliographic Details
Main Authors: Adrián A. Heredia, Martín G. López-Vidal, Marcela Kurina-Sanz, Fabricio R. Bisogno, Alicia B. Peñéñory
Format: Article
Language:English
Published: Beilstein-Institut 2019-02-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.15.34