Requirement for ω and (ω–1)-hydroxylations of fatty acids by human cytochromes P450 2E1 and 4A11

Human liver microsomes and recombinant human P450 have been used as enzyme source in order to better understand the requirement for the optimal rate of ω and (ω–1)-hydroxylations of fatty acids by cytochromes P450 2E1 and 4A. Three parameters were studied: alkyl chain length, presence and configurat...

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Bibliographic Details
Main Authors: F. Adas, J.P. Salaün, F. Berthou, D. Picart, B. Simon, Y. Amet
Format: Article
Language:English
Published: Elsevier 1999-11-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520324226