Targeting agr- and agr-Like Quorum Sensing Systems for Development of Common Therapeutics to Treat Multiple Gram-Positive Bacterial Infections

Invasive infection by the Gram-positive pathogen Staphylococcus aureus is controlled by a four gene operon, agr that encodes a quorum sensing system for the regulation of virulence. While agr has been well studied in S. aureus, the contribution of agr homologues and analogues in other Gram-positive...

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Bibliographic Details
Main Authors: Hattie Gresham, Pamela Hall, Brian Gray
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/13/4/5130