Proteome response at the edge of protein aggregation

Proteins adopt defined structures and are crucial to most cellular functions. Their misfolding and aggregation is associated with numerous degenerative human disorders such as type II diabetes, Huntington's or Alzheimer's diseases. Here, we aim to understand why cells promote the formation...

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Bibliographic Details
Main Authors: Natalia Sanchez de Groot, Ricardo A. Gomes, Anna Villar-Pique, M. Madan Babu, Ana Varela Coelho, Salvador Ventura
Format: Article
Language:English
Published: The Royal Society 2015-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.140221