Hirsutella sinensis Attenuates Aristolochic Acid-Induced Renal Tubular Epithelial-Mesenchymal Transition by Inhibiting TGF-β1 and Snail Expression.

Hirsutella sinensis Attenuates Aristolochic Acid-Induced Renal Tubular Epithelial-Mesenchymal Transition by Inhibiting TGF-β1 and Snail Expression.

OBJECTIVE:To investigate the inhibitory effect of Hirsutella sinensis (HS) on epithelial-mesenchymal transition (EMT) of renal tubular epithelial cells induced by aristolochic acid (AA) and its possible mechanism. METHODS:18 male Sprague-Dawley rats were randomly and equally divided into the followi...

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Bibliographic Details
Main Authors: Xiao-Yi Xu, Jing-Jing Chai, Yi-Pu Chen, Hong-Liang Rui, Yan-Yan Wang, Hong-Rui Dong, Yu-Lin Man, Hong Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4759455?pdf=render

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http://europepmc.org/articles/PMC4759455?pdf=render

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