Association of TILs with clinical parameters, Recurrence Score® results, and prognosis in patients with early HER2-negative breast cancer (BC)—a translational analysis of the prospective WSG PlanB trial

Association of TILs with clinical parameters, Recurrence Score® results, and prognosis in patients with early HER2-negative breast cancer (BC)—a translational analysis of the prospective WSG PlanB trial

Abstract Background The presence of tumor-infiltrating lymphocytes has been associated with prognosis and chemotherapy response, particularly in high-risk breast cancer subtypes. There is limited data so far as to (i) how tumor-infiltrating lymphocyte (TIL) measurements correlate with genomic measur...

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Bibliographic Details
Main Authors: Cornelia Kolberg-Liedtke, Gluz Oleg, Heinisch Fred, Feuerhake Friedrich, Kreipe Hans, Clemens Michael, Nuding Benno, Malter Wolfram, Reimer Toralf, Wuerstlein Rachel, Graeser Monika, Shak Steve, Nitz Ulrike, Kates Ronald, Christgen Matthias, Harbeck Nadia
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Breast Cancer Research
Subjects:
Tumor-infiltrating lymphocytes (TILs)
Adjuvant chemotherapy
Breast cancer
Disease-free survival
Hormone receptor status
Online Access:http://link.springer.com/article/10.1186/s13058-020-01283-w

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http://link.springer.com/article/10.1186/s13058-020-01283-w

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