Expression of aldehyde dehydrogenase after neoadjuvant chemotherapy is associated with expression of hypoxia-inducible factors 1 and 2 alpha and predicts prognosis in locally advanced breast cancer

Expression of aldehyde dehydrogenase after neoadjuvant chemotherapy is associated with expression of hypoxia-inducible factors 1 and 2 alpha and predicts prognosis in locally advanced breast cancer

OBJECTIVE: To analyze the expression of hypoxia-inducible factors (hypoxia-inducible factor 1A and hypoxia-inducible factor 2A) and aldehyde dehydrogenase proteins in patients with locally advanced breast carcinoma who were subjected to neoadjuvant chemotherapy. METHODS: We included 90 patients with...

Full description

Bibliographic Details
Main Authors:	Daniel Guimarães Tiezzi, Willian Simões Clagnan, Larissa Raquel Mouro Mandarano, Christiani Bisinoto de Sousa, Heitor Ricardo Cosiski Marana, Marcelo Guimarães Tiezzi, Jurandyr Moreira de Andrade
Format:	Article
Language:	English
Published:	Faculdade de Medicina / USP 2013-05-01
Series:	Clinics
Subjects:	Breast Cancer Neoadjuvant Chemotherapy Prognostic Factors
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013000500592

Similar Items

Predictive and prognostic value of ZEB1 protein expression in breast cancer patients with neoadjuvant chemotherapy
by: Ziping Wu, et al.
Published: (2019-03-01)

Prognostic Value of Interval Between the Initiation of Neoadjuvant Treatment to Surgery for Patients With Locally Advanced Rectal Cancer Following Neoadjuvant Chemotherapy, Radiotherapy and Definitive Surgery
by: Xiang-Bo Wan, et al.
Published: (2020-08-01)

Prospective Assessment of Systemic MicroRNAs as Markers of Response to Neoadjuvant Chemotherapy in Breast Cancer
by: Andrew McGuire, et al.
Published: (2020-07-01)

Mouse renal 4T1 cell engraftment as a model to study the influence of hypoxia in breast cancer progression
by: Heriton Marcelo Ribeiro Antonio, et al.
Published: (2013-02-01)

Expression of Hypoxia-inducible factor 1-α and Vascular endothelial growth factor-C in locally advanced breast cancer patients
by: Luiz Gustavo Oliveira Brito, et al.
Published: (2011-01-01)

Tumor budding outperforms ypT and ypN classification in predicting outcome of rectal cancer after neoadjuvant chemoradiotherapy
by: Iryna Trotsyuk, et al.
Published: (2019-11-01)

HER-2, p53, p21 and hormonal receptors proteins expression as predictive factors of response and prognosis in locally advanced breast cancer treated with neoadjuvant docetaxel plus epirubicin combination
by: Tiezzi Marcelo G, et al.
Published: (2007-02-01)

Prognostic Nutritional Index (PNI) in Patients With Breast Cancer Treated With Neoadjuvant Chemotherapy as a Useful Prognostic Indicator
by: Li Chen, et al.
Published: (2021-03-01)

A novel LARCassigner3 classification predicts outcomes in patients with locally advanced rectal cancer treated with neoadjuvant chemoradiotherapy: a retrospective training and validation analysis
by: Zhang J, et al.
Published: (2019-05-01)

MICROARRAY ANALYSIS OF DNA COPY NUMBER ABERRATION IN BREAST TUMOR: CORRELATION WITH THE EFFICACY OF NEOADJUVANT CHEMOTHERAPY
by: N. V. Litviakov, et al.
Published: (2016-02-01)

Neoadjuvant chemotherapy-induced decrease of prognostic nutrition index predicts poor prognosis in patients with breast cancer
by: Takaaki Oba, et al.
Published: (2020-02-01)

Neoadjuvant Treatment in Pancreatic Cancer
by: Atsushi Oba, et al.
Published: (2020-02-01)

State of the art of neoadjuvant chemotherapy in breast cancer: rationale, results and recent developments
by: Solomayer, Erich-Franz, et al.
Published: (2005-09-01)

Predictive and prognostic value of Matrix metalloproteinase (MMP) - 9 in neoadjuvant chemotherapy for triple-negative breast cancer patients
by: Ruo-Xi Wang, et al.
Published: (2018-09-01)

Expression of Bcl-2 in Breast Cancer: Correlation with Clinicopathological Characteristics and Survival
by: Filip Čečka, et al.
Published: (2008-01-01)

History and current situation of neoadjuvant treatment for locally advanced esophageal cancer
by: Junyi Li, et al.
Published: (2021-09-01)

Analysis of the Curative Effect of Neoadjuvant Therapy on Pancreatic Cancer
by: Liqiong Yang, et al.
Published: (2021-08-01)

Neoadjuvant Systemic Treatment of Primary Angiosarcoma
by: Kimberley M. Heinhuis, et al.
Published: (2020-08-01)

Prognostic Value of Plasma Epstein-Barr Virus DNA Levels Pre- and Post-Neoadjuvant Chemotherapy in Patients With Nasopharyngeal Carcinoma
by: Lisheng Zhu, et al.
Published: (2021-09-01)

Associação entre a expressão e a função da enzima ALDH1 no câncer de mama
by: Mandarano, Larissa Raquel Mouro
Published: (2018)

The Immunoscore in Localized Urothelial Carcinoma Treated with Neoadjuvant Chemotherapy: Clinical Significance for Pathologic Responses and Overall Survival
by: Elise F. Nassif, et al.
Published: (2021-01-01)

Elevated platelet count is a negative predictive and prognostic marker in locally advanced rectal cancer undergoing neoadjuvant chemoradiation: a retrospective multi-institutional study on 965 patients
by: Claudio Belluco, et al.
Published: (2018-11-01)

Efficacy and safety of cisplatin and paclitaxel (PlaTax regimen) in the neoadjuvant treatment of patients with stage II–III triple-negative breast cancer
by: O. O. Gordeeva, et al.
Published: (2020-11-01)

Meta-analysis of neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for locally advanced rectal cancer
by: Huaqin Lin, et al.
Published: (2021-05-01)

Prognostic Relevance of Neutrophil to Lymphocyte Ratio (NLR) in Luminal Breast Cancer: A Retrospective Analysis in the Neoadjuvant Setting
by: Antonino Grassadonia, et al.
Published: (2021-07-01)

Long-term outcomes of neoadjuvant chemotherapy followed by concurrent chemoradiotherapy (CCRT) vs CCRT alone for nasopharyngeal carcinoma in the era of intensity-modulated radiation therapy using propensity score matching method
by: Chen X, et al.
Published: (2017-06-01)

The Prognostic Value of Lymph Node Involvement after Neoadjuvant Chemotherapy Is Different among Breast Cancer Subtypes
by: Lucie Laot, et al.
Published: (2021-01-01)

Dihydropyrimidine dehydrogenase mutation in neoadjuvant chemotherapy in head and neck cancers: Myth or reality?
by: Vijay M Patil, et al.
Published: (2016-01-01)

Neoadjuvant and Adjuvant Chemotherapy in Osteosarcoma (The Experience of HORC in the Shariati Hospital)
by: Alimoghadam K, et al.
Published: (2004-07-01)

The Effect of Neoadjuvant Chemotherapy on HIF-1α Expression in Cervical Uterine Cancer
by: Ika Wiraswesty, et al.
Published: (2018-06-01)

Neoadjuvant strategies in resectable carcinoma esophagus: a meta-analysis of randomized trials
by: Tarun Kumar, et al.
Published: (2020-03-01)

Neoadjuvant chemotherapy with trastuzumab in HER2-positive breast cancer: pathologic complete response rate, predictive and prognostic factors
by: I.P.C. Buzatto, et al.

Neoadjuvant treatment for breast cancer
by: V. F. Semiglazov, et al.
Published: (2014-07-01)

Miller–Payne Grading and 70-Gene Signature Are Associated With Prognosis of Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Early-Stage Breast Cancer After Neoadjuvant Chemotherapy
by: Liye Wang, et al.
Published: (2021-09-01)

Idade como fator independente de prognóstico no câncer de mama Age as an independent prognostic factor in breast cancer
by: Willian Simões Clagnan, et al.
Published: (2008-02-01)

miRNA expression changes during the course of neoadjuvant bevacizumab and chemotherapy treatment in breast cancer
by: Evita Maria Lindholm, et al.
Published: (2019-10-01)

Inflammatory Blood Markers as Prognostic and Predictive Factors in Early Breast Cancer Patients Receiving Neoadjuvant Chemotherapy
by: Ileana Corbeau, et al.
Published: (2020-09-01)

Neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for locally advanced oesophageal squamous cell carcinoma: a single-Centre, open-label, randomized, controlled, clinical trial (HCHTOG1903)
by: Hai-Bo Sun, et al.
Published: (2020-04-01)

Approaching Neoadjuvant Therapy in the Management of Early-Stage Breast Cancer
by: Hyder T, et al.
Published: (2021-03-01)

Neoadjuvant treatment for resectable pancreatic adenocarcinoma: What is the best protocol?
by: Fuyuhiko Motoi, et al.
Published: (2020-03-01)