Expression of aldehyde dehydrogenase after neoadjuvant chemotherapy is associated with expression of hypoxia-inducible factors 1 and 2 alpha and predicts prognosis in locally advanced breast cancer

Expression of aldehyde dehydrogenase after neoadjuvant chemotherapy is associated with expression of hypoxia-inducible factors 1 and 2 alpha and predicts prognosis in locally advanced breast cancer

OBJECTIVE: To analyze the expression of hypoxia-inducible factors (hypoxia-inducible factor 1A and hypoxia-inducible factor 2A) and aldehyde dehydrogenase proteins in patients with locally advanced breast carcinoma who were subjected to neoadjuvant chemotherapy. METHODS: We included 90 patients with...

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Bibliographic Details
Main Authors: Daniel Guimarães Tiezzi, Willian Simões Clagnan, Larissa Raquel Mouro Mandarano, Christiani Bisinoto de Sousa, Heitor Ricardo Cosiski Marana, Marcelo Guimarães Tiezzi, Jurandyr Moreira de Andrade
Format: Article
Language:English
Published: Faculdade de Medicina / USP 2013-05-01
Series:Clinics
Subjects:
Breast Cancer
Neoadjuvant Chemotherapy
Prognostic Factors
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013000500592

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013000500592

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