Optimization of the Expression of DT386-BR2 Fusion Protein in Escherichia coli using Response Surface Methodology

Optimization of the Expression of DT386-BR2 Fusion Protein in Escherichia coli using Response Surface Methodology

Background: The aim of this study was to determine the best condition for the production of DT386-BR2 fusion protein, an immunotoxin consisting of catalytic and translocation domains of diphtheria toxin fused to BR2, a cancer specific cell penetrating peptide, for targeted eradication of cancer cell...

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Bibliographic Details
Main Authors: Fatemeh Shafiee, Mohammad Rabbani, Ali Jahanian-Najafabadi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-01-01
Series:Advanced Biomedical Research
Subjects:
DT386-BR2
expression
optimization
response surface methodology
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2017;volume=6;issue=1;spage=22;epage=22;aulast=Shafiee

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http://www.advbiores.net/article.asp?issn=2277-9175;year=2017;volume=6;issue=1;spage=22;epage=22;aulast=Shafiee

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