The N-terminal Helical Region of the Hepatitis C Virus p7 Ion Channel Protein Is Critical for Infectious Virus Production.

The N-terminal Helical Region of the Hepatitis C Virus p7 Ion Channel Protein Is Critical for Infectious Virus Production.

The hepatitis C virus (HCV) p7 protein is required for infectious virus production via its role in assembly and ion channel activity. Although NMR structures of p7 have been reported, the location of secondary structural elements and orientation of the p7 transmembrane domains differ among models. F...

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Bibliographic Details
Main Authors: Margaret A Scull, William M Schneider, Brenna R Flatley, Robert Hayden, Canny Fung, Christopher T Jones, Marieke van de Belt, François Penin, Charles M Rice
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4654572?pdf=render

Internet

http://europepmc.org/articles/PMC4654572?pdf=render

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