Autologous bone-marrow mesenchymal stem cell implantation and endothelial function in a rabbit ischemic limb model.

BACKGROUND: The purpose of this study was to determine whether autologous mesenchymal stem cells (MSCs) implantation improves endothelial dysfunction in a rabbit ischemic limb model. METHODS: We evaluated the effect of MSC implantation on limb blood flow (LBF) responses to acetylcholine (ACh), an en...

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Bibliographic Details
Main Authors: Shinsuke Mikami, Ayumu Nakashima, Keigo Nakagawa, Tatsuya Maruhashi, Yumiko Iwamoto, Masato Kajikawa, Takeshi Matsumoto, Yasuki Kihara, Kazuaki Chayama, Kensuke Noma, Mitsuo Ochi, Masahiro Nishimura, Koichiro Tsuji, Yukio Kato, Chikara Goto, Yukihito Higashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3701528?pdf=render