Alterations at the peptidyl transferase centre of the ribosome induced by the synergistic action of the streptogramins dalfopristin and quinupristin

<p>Abstract</p> <p>Background</p> <p>The bacterial ribosome is a primary target of several classes of antibiotics. Investigation of the structure of the ribosomal subunits in complex with different antibiotics can reveal the mode of inhibition of ribosomal protein synth...

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Bibliographic Details
Main Authors: Fucini Paola, Schlünzen Frank, Harms Jörg M, Bartels Heike, Yonath Ada
Format: Article
Language:English
Published: BMC 2004-04-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/2/4