Chronic Intra-Uterine Ureaplasma parvum Infection Induces Injury of the Enteric Nervous System in Ovine Fetuses

Chronic Intra-Uterine Ureaplasma parvum Infection Induces Injury of the Enteric Nervous System in Ovine Fetuses

Background: Chorioamnionitis, inflammation of the fetal membranes during pregnancy, is often caused by intra-amniotic (IA) infection with single or multiple microbes. Chorioamnionitis can be either acute or chronic and is associated with adverse postnatal outcomes of the intestine, including necroti...

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Main Authors: Cathelijne Heymans, Ilse H. de Lange, Matthias C. Hütten, Kaatje Lenaerts, Nadine J. E. de Ruijter, Lilian C. G. A. Kessels, Glenn Rademakers, Veerle Melotte, Werend Boesmans, Masatoshi Saito, Haruo Usuda, Sarah J. Stock, Owen B. Spiller, Michael L. Beeton, Matthew S. Payne, Boris W. Kramer, John P. Newnham, Alan H. Jobe, Matthew W. Kemp, Wim G. van Gemert, Tim G. A. M. Wolfs
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
Ureaplasma parvum
intra-amniotic infection
chorioamnionitis
enteric nervous system
sheep
preterm birth
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00189/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.00189/full

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