Electronic Structures of LNA Phosphorothioate Oligonucleotides

Electronic Structures of LNA Phosphorothioate Oligonucleotides

Important oligonucleotides in anti-sense research have been investigated in silico and experimentally. This involves quantum mechanical (QM) calculations and chromatography experiments on locked nucleic acid (LNA) phosphorothioate (PS) oligonucleotides. iso-potential electrostatic surfaces are essen...

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Bibliographic Details
Main Authors:	Henrik G. Bohr, Irene Shim, Cy Stein, Henrik Ørum, Henrik F. Hansen, Troels Koch
Format:	Article
Language:	English
Published:	Elsevier 2017-09-01
Series:	Molecular Therapy: Nucleic Acids
Online Access:	http://www.sciencedirect.com/science/article/pii/S2162253117301828

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