Electronic Structures of LNA Phosphorothioate Oligonucleotides

by Henrik G. Bohr, Irene Shim, Cy Stein, Henrik Ørum, Henrik F. Hansen, Troels Koch
Published 2017-09-01

A locked nucleic acid antisense oligonucleotide (LNA) silences PCSK9 and enhances LDLR expression in vitro and in vivo.

by Nidhi Gupta, Niels Fisker, Marie-Claude Asselin, Marie Lindholm, Christoph Rosenbohm, Henrik Ørum, Joacim Elmén, Nabil G Seidah, Ellen Marie Straarup
Published 2010-05-01