Tissue and cellular specific expression of murine lysosomal acid lipase mRNA and protein

Lysosomal acid lipase (LAL) is essential to the intracellular control of cholesterol and triglyceride catabolism via the low density lipoprotein (LDL) delivery of these neutral lipids to the lysosome. Deficiency of LAL in humans leads to Wolman disease and cholesteryl ester storage disease that resu...

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Bibliographic Details
Main Authors: H Du, D P Witte, G A Grabowski
Format: Article
Language:English
Published: Elsevier 1996-05-01
Series:Journal of Lipid Research
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752042005X