Intermittent High Glucose Exacerbates A-FABP Activation and Inflammatory Response through TLR4-JNK Signaling in THP-1 Cells

Background. Glucose fluctuation confers additional risks on diabetes-related vascular diseases, but the underlying mechanisms are unknown. Macrophage activation mediated by TLR4-JNK signaling plays an important role during the progress of diabetes. In the present study, we hypothesize that glucose f...

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Bibliographic Details
Main Authors: Hui Li, Han-Ying Luo, Qing Liu, Yang Xiao, Lin Tang, Feng Zhong, Gan Huang, Jun-Mei Xu, Ai-Min Xu, Zhi-Guang Zhou, Ru-Ping Dai
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2018/1319272