The elongator complex interacts with PCNA and modulates transcriptional silencing and sensitivity to DNA damage agents.
Histone chaperones CAF-1 and Asf1 function to deposit newly synthesized histones onto replicating DNA to promote nucleosome formation in a proliferating cell nuclear antigen (PCNA) dependent process. The DNA replication- or DNA repair-coupled nucleosome assembly pathways are important for maintenanc...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2009-10-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2757915?pdf=render |