Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38
The ATF2 transcription factor is phosphorylated by different mitogen-activated protein (MAP) kinases. Here, the authors show that the functionally distinct MAP kinases JNK and p38 control ATF2 through different binding sites and differential phosphorylation, thereby modulating ATF2’s sensitivity to...
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Bibliographic Details
| Main Authors: |
Klára Kirsch,
András Zeke,
Orsolya Tőke,
Péter Sok,
Ashish Sethi,
Anna Sebő,
Ganesan Senthil Kumar,
Péter Egri,
Ádám L. Póti,
Paul Gooley,
Wolfgang Peti,
Isabel Bento,
Anita Alexa,
Attila Reményi |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2020-11-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-19582-3
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