Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38

Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38

The ATF2 transcription factor is phosphorylated by different mitogen-activated protein (MAP) kinases. Here, the authors show that the functionally distinct MAP kinases JNK and p38 control ATF2 through different binding sites and differential phosphorylation, thereby modulating ATF2’s sensitivity to...

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Bibliographic Details
Main Authors: Klára Kirsch, András Zeke, Orsolya Tőke, Péter Sok, Ashish Sethi, Anna Sebő, Ganesan Senthil Kumar, Péter Egri, Ádám L. Póti, Paul Gooley, Wolfgang Peti, Isabel Bento, Anita Alexa, Attila Reményi
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19582-3

Internet

https://doi.org/10.1038/s41467-020-19582-3

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