Development of a Japanese encephalitis virus-like particle vaccine in silkworms using codon-optimised prM and envelope genes

Development of a Japanese encephalitis virus-like particle vaccine in silkworms using codon-optimised prM and envelope genes

We have successfully prepared a Japanese encephalitis virus (JEV) − Nakayama virus like particle (NVLP) vaccine using synthetic codon-optimized prM and E genes. The expression of the recombinant JEV Nakayama-BmNPV (JEV-NNPV) virus was determined in infected silkworm Bm-N cells by fluorescence and We...

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Bibliographic Details
Main Authors: Sayaka Matsuda, Reiko Nerome, Kenichi Maegawa, Akira Kotaki, Shigeo Sugita, Kazunori Kawasaki, Kazumichi Kuroda, Ryoji Yamaguchi, Tomohiko Takasaki, Kuniaki Nerome
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Heliyon
Subjects:
Immunology
Vaccines
Infectious disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844016323453

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http://www.sciencedirect.com/science/article/pii/S2405844016323453

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