Loregic: a method to characterize the cooperative logic of regulatory factors.

The topology of the gene-regulatory network has been extensively analyzed. Now, given the large amount of available functional genomic data, it is possible to go beyond this and systematically study regulatory circuits in terms of logic elements. To this end, we present Loregic, a computational meth...

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Bibliographic Details
Main Authors: Daifeng Wang, Koon-Kiu Yan, Cristina Sisu, Chao Cheng, Joel Rozowsky, William Meyerson, Mark B Gerstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-04-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004132