A drug-sensitive genetic network masks fungi from the immune system.
Fungal pathogens can be recognized by the immune system via their beta-glucan, a potent proinflammatory molecule that is present at high levels but is predominantly buried beneath a mannoprotein coat and invisible to the host. To investigate the nature and significance of "masking" this mo...
Format: | Article |
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Language: | English |
Published: |
Public Library of Science (PLoS)
2006-04-01
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Series: | PLoS Pathogens |
Online Access: | http://dx.doi.org/10.1371/journal.ppat.0020035 |