Mitochondrial pyruvate carrier 1: a novel prognostic biomarker that predicts favourable patient survival in cancer

Abstract Mitochondrial pyruvate carrier 1 (MPC1) is a key metabolic protein that regulates the transport of pyruvate into the mitochondrial inner membrane. MPC1 deficiency may cause metabolic reprogramming. However, whether and how MPC1 controls mitochondrial oxidative capacity in cancer are still r...

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Bibliographic Details
Main Authors: Chen Xue, Ganglei Li, Zhengyi Bao, Ziyuan Zhou, Lanjuan Li
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-021-01996-8