Thymoquinone, but Not Metformin, Protects against Gentamicin-Induced Nephrotoxicity and Renal Dysfunction in Rats

Thymoquinone, but Not Metformin, Protects against Gentamicin-Induced Nephrotoxicity and Renal Dysfunction in Rats

Background: Gentamicin (GM) is an antibiotic that is widely used to treat many Gram-negative bacteria, such as those involved in urinary tract infections. However, being nephrotoxic, GM dose adjustment and reno-protective elements must be concurrently administered with GM to minimize kidney damage....

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Bibliographic Details
Main Authors: Mansour Alsharidah, Abdel-Moneim Hafez Abdel-Moneim, Ashwag Saleh Alsharidah, Mugahid A. Mobark, Arshad Husain Rahmani, Ahmed Shata, Ahmed A. H. Abdellatif, Mahmoud Zaki El-Readi, Khalid M. Mohany, Osamah Al Rugaie
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Applied Sciences
Subjects:
nephrotoxicity
gentamicin
thymoquinone
metformin
oxidative stress
Online Access:https://www.mdpi.com/2076-3417/11/9/3981

Internet

https://www.mdpi.com/2076-3417/11/9/3981

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