Aromatic-Turmerone Analogs Protect Dopaminergic Neurons in Midbrain Slice Cultures through Their Neuroprotective Activities

Aromatic-Turmerone Analogs Protect Dopaminergic Neurons in Midbrain Slice Cultures through Their Neuroprotective Activities

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra. The inflammatory activation of microglia participates in dopaminergic neurodegeneration in PD. Therefore, chemicals that inhibit microglial activation are considered to...

Full description

Bibliographic Details
Main Authors: Yuria Hori, Reiho Tsutsumi, Kento Nasu, Alex Boateng, Yasuhiko Ashikari, Masaharu Sugiura, Makoto Nakajima, Yuki Kurauchi, Akinori Hisatsune, Hiroshi Katsuki, Takahiro Seki
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cells
Subjects:
aromatic-turmerone
dopaminergic neurons
microglia
Nrf2
Online Access:https://www.mdpi.com/2073-4409/10/5/1090

Internet

https://www.mdpi.com/2073-4409/10/5/1090

Similar Items