Periostin contributes to the acquisition of multipotent stem cell-like properties in human mammary epithelial cells and breast cancer cells.

Periostin (POSTN), a recently characterised matricellular protein, is frequently dysregulated in various malignant cancers and promotes tumor metastatic growth. POSTN plays a critical role in the crosstalk between murine breast cancer stem cells (CSCs) and their niche to permit metastatic colonizati...

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Bibliographic Details
Main Authors: Xiaowei Wang, Jia Liu, Zhe Wang, Yangmei Huang, Weiping Liu, Xiao Zhu, Yao Cai, Xiaoguang Fang, Shuyong Lin, Li Yuan, Gaoliang Ouyang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3756944?pdf=render