In vivo fluorescence-based endoscopic detection of colon dysplasia in the mouse using a novel peptide probe.

Colorectal cancer (CRC) is a major cause of cancer-related deaths in much of the world. Most CRCs arise from pre-malignant (dysplastic) lesions, such as adenomatous polyps, and current endoscopic screening approaches with white light do not detect all dysplastic lesions. Thus, new strategies to iden...

Full description

Bibliographic Details
Main Authors: Sharon J Miller, Bishnu P Joshi, Ying Feng, Adam Gaustad, Eric R Fearon, Thomas D Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3050896?pdf=render