Blockage of C-X-C Motif Chemokine Receptor 2 (CXCR2) Suppressed Uric Acid (UA)-Induced Cardiac Remodeling

Blockage of C-X-C Motif Chemokine Receptor 2 (CXCR2) Suppressed Uric Acid (UA)-Induced Cardiac Remodeling

Hyperuricemia-induced cardiac remodeling is at least in part via pressure-dependent mechanisms, yet the pressure-independent mechanisms are not well understood. C-X-C motif chemokine ligand 1 (CXCL1) was upregulated in renal tubules from mice subjected to uric acid (UA)-induced nephropathy. Given th...

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Bibliographic Details
Main Authors: Mingxi Xu, Xu Zheng, Dongxia Wang, Xiaodan Fu, Yida Xing, Yu Liu, Hongjiang Wang, Xiaodan Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Physiology
Subjects:
CXCL1
CXCL2
uric acid
inflammation
migration
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.700338/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.700338/full

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