Protein kinase C-α (PKCα) modulates cell apoptosis by stimulating nuclear translocation of NF-kappa-B p65 in urothelial cell carcinoma of the bladder

Protein kinase C-α (PKCα) modulates cell apoptosis by stimulating nuclear translocation of NF-kappa-B p65 in urothelial cell carcinoma of the bladder

Abstract Background The protein kinase C (PKC) family comprises central regulators of multiple signal transduction processes and is involved in the progression of many cancers. Nuclear factor Kappa-B (NF-κB) is constitutively expressed in cancer tissues and stimulates the transcription of various tu...

Full description

Bibliographic Details
Main Authors: Jin Zheng, Chuize Kong, Xiaoxi Yang, Xiaolu Cui, Xuyong Lin, Zhe Zhang
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Cancer
Subjects:
PKCα
NF-κB
Urothelial cell cancer
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12885-017-3401-7

Internet

http://link.springer.com/article/10.1186/s12885-017-3401-7

Similar Items