Structural analysis of viral ExoN domains reveals polyphyletic hijacking events.

Structural analysis of viral ExoN domains reveals polyphyletic hijacking events.

Nidoviruses and arenaviruses are the only known RNA viruses encoding a 3'-5' exonuclease domain (ExoN). The proofreading activity of the ExoN domain has played a key role in the growth of nidoviral genomes, while in arenaviruses this domain partakes in the suppression of the host innate im...

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Bibliographic Details
Main Authors: Adrián Cruz-González, Israel Muñoz-Velasco, Wolfgang Cottom-Salas, Arturo Becerra, José A Campillo-Balderas, Ricardo Hernández-Morales, Alberto Vázquez-Salazar, Rodrigo Jácome, Antonio Lazcano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0246981

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https://doi.org/10.1371/journal.pone.0246981

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