Structure and Glass Transition Temperature of Amorphous Dispersions of Model Pharmaceuticals with Nucleobases from Molecular Dynamics

Structure and Glass Transition Temperature of Amorphous Dispersions of Model Pharmaceuticals with Nucleobases from Molecular Dynamics

Glass transition temperature (<i>T</i><sub>g</sub>) is an important material property, which predetermines the kinetic stability of amorphous solids. In the context of active pharmaceutical ingredients (API), there is motivation to maximize their <i>T</i><sub&g...

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Bibliographic Details
Main Authors: Ctirad Červinka, Michal Fulem
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
active pharmaceutical ingredients
amorphous dispersion
glass transition
molecular dynamics
Online Access:https://www.mdpi.com/1999-4923/13/8/1253

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https://www.mdpi.com/1999-4923/13/8/1253

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