Deguelin, an Aurora B Kinase Inhibitor, Exhibits Potent Anti-Tumor Effect in Human Esophageal Squamous Cell Carcinoma

Aurora B kinase has emerged as a key regulator of mitosis and deregulation of Aurora B activity is closely related to the development and progression of human cancers. In the present study, we found that Aurora B is overexpressed in human esophageal squamous cell carcinoma (ESCC), high levels of Aur...

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Bibliographic Details
Main Authors: Xinfang Yu, Qi Liang, Wenbin Liu, Li Zhou, Wei Li, Haidan Liu
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S235239641730436X