Surgical protocol for permanent ligation of the left anterior descending coronary artery in mice to generate a model of myocardial infarction

Summary: Myocardial infarction (MI) is one of the most common causes of death worldwide. Animal models for MI are useful for studying the pathophysiology and developing therapies. Here, we describe a surgical protocol for permanent ligation of the left anterior descending coronary artery in mice, wh...

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Bibliographic Details
Main Authors: Kazuaki Maruyama, Kazuaki Naemura, Kenji Yoshihara, Kyoko Imanaka-Yoshida, Hiroki Kurihara, Sachiko Miyagawa-Tomita
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721004810