DSPP-MMP20 gene silencing downregulates cancer stem cell markers in human oral cancer cells

DSPP-MMP20 gene silencing downregulates cancer stem cell markers in human oral cancer cells

Abstract Background Recent findings indicate that dentin sialophosphoprotein (DSPP) and matrix metalloproteinase (MMP) 20 interact in oral squamous cell carcinoma (OSCC). The objective of this study was to determine the effects of DSPP/MMP20 gene silencing on oral cancer stem cell (OCSC) markers. Me...

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Bibliographic Details
Main Authors: Nikolaos G. Nikitakis, Ioannis Gkouveris, Jaya Aseervatham, Kelvin Barahona, Kalu U. E. Ogbureke
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Cellular & Molecular Biology Letters
Subjects:
Cancer stem cells
Cancer stem cell markers
Oral Cancer
OSCC
MMP20
DSPP
Online Access:http://link.springer.com/article/10.1186/s11658-018-0096-y

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http://link.springer.com/article/10.1186/s11658-018-0096-y

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