Influence of spacer length on heparin coupling efficiency and fibrinogen adsorption of modified titanium surfaces

<p>Abstract</p> <p>Background</p> <p>Chemical bonding of the drug onto surfaces by means of spacer molecules is accompanied with a reduction of the biological activity of the drug due to a constricted mobility since normally only short spacer molecule like aminopropyltr...

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Bibliographic Details
Main Authors: Gbureck Uwe, Thull Roger, Tebbe David
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BioMedical Engineering OnLine
Online Access:http://www.biomedical-engineering-online.com/content/6/1/31