Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors

Summary: Human embryonic stem cells (hESCs) are a potential unlimited source of insulin-producing β cells for diabetes treatment. A greater understanding of how β cells form during embryonic development will improve current hESC differentiation protocols. All pancreatic endocrine cells, including β...

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Bibliographic Details
Main Authors: Nicole A.J. Krentz, Michelle Y.Y. Lee, Eric E. Xu, Shannon L.J. Sproul, Alexandra Maslova, Shugo Sasaki, Francis C. Lynn
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118304764