Mitochondrial Carriers Link the Catabolism of Hydroxyaromatic Compounds to the Central Metabolism in Candida parapsilosis

Mitochondrial Carriers Link the Catabolism of Hydroxyaromatic Compounds to the Central Metabolism in Candida parapsilosis

The pathogenic yeast Candida parapsilosis metabolizes hydroxyderivatives of benzene and benzoic acid to compounds channeled into central metabolism, including the mitochondrially localized tricarboxylic acid cycle, via the 3-oxoadipate and gentisate pathways. The orchestration of both catabolic path...

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Bibliographic Details
Main Authors: Igor Zeman, Martina Neboháčová, Gabriela Gérecová, Kornélia Katonová, Eva Jánošíková, Michaela Jakúbková, Ivana Centárová, Ivana Dunčková, L'ubomír Tomáška, Leszek P. Pryszcz, Toni Gabaldón, Jozef Nosek
Format: Article
Language:English
Published: Oxford University Press 2016-12-01
Series:G3: Genes, Genomes, Genetics
Subjects:
gentisate pathway
3-oxoadipate pathway
catabolism of hydroxybenzoates
mitochondrial carrier
evolution of biochemical pathways
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.034389

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http://g3journal.org/lookup/doi/10.1534/g3.116.034389

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