Single-Cell Analysis of Different Stages of Oral Cancer Carcinogenesis in a Mouse Model

Single-Cell Analysis of Different Stages of Oral Cancer Carcinogenesis in a Mouse Model

Oral carcinogenesis involves the progression of the normal mucosa into potentially malignant disorders and finally into cancer. Tumors are heterogeneous, with different clusters of cells expressing different genes and exhibiting different behaviors. 4-nitroquinoline 1-oxide (4-NQO) and arecoline wer...

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Bibliographic Details
Main Authors: Ling-Yu Huang, Yi-Ping Hsieh, Yen-Yun Wang, Daw-Yang Hwang, Shih Sheng Jiang, Wen-Tsung Huang, Wei-Fan Chiang, Ko-Jiunn Liu, Tze-Ta Huang
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
mouse model
carcinogenesis
single-cell RNA sequencing
oral cancer
Online Access:https://www.mdpi.com/1422-0067/21/21/8171

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https://www.mdpi.com/1422-0067/21/21/8171

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