A novel porcine in vitro model of the blood-cerebrospinal fluid barrier with strong barrier function.

Epithelial cells of the plexus choroideus form the structural basis of the blood-cerebrospinal fluid barrier (BCSFB). In vitro models of the BCSFB presenting characteristics of a functional barrier are of significant scientific interest as tools for examination of BCSFB function. Due to a lack of su...

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Bibliographic Details
Main Authors: Mira Schroten, Franz-Georg Hanisch, Natascha Quednau, Carolin Stump, Roland Riebe, Matthias Lenk, Hartwig Wolburg, Tobias Tenenbaum, Christian Schwerk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3382175?pdf=render