Vascular endothelial expression of indoleamine 2,3-dioxygenase 1 forms a positive gradient towards the feto-maternal interface.

We describe the distribution of indoleamine 2,3-dioxygenase 1 (IDO1) in vascular endothelium of human first-trimester and term placenta. Expression of IDO1 protein on the fetal side of the interface extended from almost exclusively sub-trophoblastic capillaries in first-trimester placenta to a nearl...

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Bibliographic Details
Main Authors: Astrid Blaschitz, Martin Gauster, Dietmar Fuchs, Ingrid Lang, Petra Maschke, Daniela Ulrich, Eva Karpf, Osamu Takikawa, Michael G Schimek, Gottfried Dohr, Peter Sedlmayr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21755000/?tool=EBI