Microvesicles from malaria-infected red blood cells activate natural killer cells via MDA5 pathway.

Natural killer (NK) cells provide the first line of defense against malaria parasite infection. However, the molecular mechanisms through which NK cells are activated by parasites are largely unknown, so is the molecular basis underlying the variation in NK cell responses to malaria infection in the...

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Bibliographic Details
Main Authors: Weijian Ye, Marvin Chew, Jue Hou, Fritz Lai, Stije J Leopold, Hooi Linn Loo, Aniruddha Ghose, Ashok K Dutta, Qingfeng Chen, Eng Eong Ooi, Nicholas J White, Arjen M Dondorp, Peter Preiser, Jianzhu Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6171940?pdf=render