Enhanced production of bovine chymosin by autophagy deficiency in the filamentous fungus Aspergillus oryzae.
Aspergillus oryzae has been utilized as a host for heterologous protein production because of its high protein secretory capacity and food-safety properties. However, A. oryzae often produces lower-than-expected yields of target heterologous proteins due to various underlying mechanisms, including d...
Main Authors: | Jaewoo Yoon, Takashi Kikuma, Jun-ichi Maruyama, Katsuhiko Kitamoto |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3639164?pdf=render |
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