Probing a polar cluster in the retinal binding pocket of bacteriorhodopsin by a chemical design approach.

Bacteriorhodopsin has a polar cluster of amino acids surrounding the retinal molecule, which is responsible for light harvesting to fuel proton pumping. From our previous studies, we have shown that threonine 90 is the pivotal amino acid in this polar cluster, both functionally and structurally. In...

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Bibliographic Details
Main Authors: Rosana Simón-Vázquez, Marta Domínguez, Víctor A Lórenz-Fonfría, Susana Alvarez, José-Luís Bourdelande, Angel R de Lera, Esteve Padrós, Alex Perálvarez-Marín
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22879987/pdf/?tool=EBI