Genetic sequence characterization and naturally acquired immune response to Plasmodium vivax Rhoptry Neck Protein 2 (PvRON2)

Genetic sequence characterization and naturally acquired immune response to Plasmodium vivax Rhoptry Neck Protein 2 (PvRON2)

Abstract Background The genetic diversity of malaria antigens often results in allele variant-specific immunity, imposing a great challenge to vaccine development. Rhoptry Neck Protein 2 (PvRON2) is a blood-stage antigen that plays a key role during the erythrocyte invasion of Plasmodium vivax. This...

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Bibliographic Details
Main Authors: Najara C. Bittencourt, Juliana A. Leite, Ana Beatriz I. E. Silva, Tamirys S. Pimenta, João Luiz Silva-Filho, Gustavo C. Cassiano, Stefanie C. P. Lopes, Joao C. K. dos-Santos, Catarina Bourgard, Helder I. Nakaya, Ana Maria Revorêdo da Silva Ventura, Marcus V. G. Lacerda, Marcelo U. Ferreira, Ricardo L. D. Machado, Letusa Albrecht, Fabio T. M. Costa
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Malaria Journal
Subjects:
Genetic diversity
RON2
Plasmodium vivax
Immunogenicity
Malaria
Online Access:http://link.springer.com/article/10.1186/s12936-018-2543-7

Internet

http://link.springer.com/article/10.1186/s12936-018-2543-7

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